Addressing some of humanity's most complex problems requires a serious facility and program promoting successful collaboration among various disciplines. Supported by a $500 million, 10-year award from BP, the Energy Biosciences Institute embodies a vast interdisciplinary research organization of 300-plus scientists dedicated to using biological tools and methods to solve global energy challenges and mitigate climate change. SmithGroup's design team worked with stakeholders and occupants to develop a flexible laboratory and office plan, accommodating the research and the work cultures of each discipline. The facility supports multidisciplinary teams dispersed throughout greenhouses, warm and cold rooms, shared instrumentation spaces, and state-of-the-art molecular biology, microbial biology, fermentation, and chemical separation laboratories. Common spaces provide connective support, keeping the focus on interaction in their welcoming lounges and informal meeting zones, which share subtle aesthetic elements with the lab facilities, such as colorful translucencies. Its LEED Gold design delivers on the facility's stated mission, too.