The Fayez S. Sarofim Research Building, home of the Brown Foundation Institute of Molecular Medicine, is a comprehensive research facility on a tight urban site within the Texas Medical Center campus. This facility is designated to support research collaboration in the area of molecular medicine, particularly in genetics and proteomics and bioinformatics. The Sarofim Research Building houses dry and wet laboratories, offices, conferencing areas, a 200-seat assembly facility, and appropriate support spaces. The design creates a dynamic, interactive environment conducive to research and learning on multiple levels. From the relationship with the outdoors, to the architecture of the building, to the interior spaces, the approach considers form and function holistically, promoting the productivity and well-being of users.