The Centre for Regenerative Medicine is a cutting-edge
international project producing adult stem cells for human tissue transplant.
The conception and dimensions of this innovative project make
it the first of its kind in Europe, requiring a completely sterile environment
– often without natural light or contact with outside air – for fifty
researchers working with advanced procedures for guaranteeing sterility and
advanced technology systems and equipment.
The Centre is characterised by its patterned exterior; a
pattern generated using the same mathematical formulas regulating biological
emergence of patterning in animal skins, sympathetically reflecting the kind of
activity taking place in the interior; and by experimental facade techniques
using polystyrene and glass fibre.
- size,
spread, function
The Centre is
a compact building measuring 40x25 metres, 13.5 metres high, divided into three
floors each totalling 1,000 metres³.
Research and
administrative/managerial spaces are situated on the ground floor (reception
areas, research studies, meeting areas, archive and consultation areas)
together with storage areas and centralised systems areas. Biochemistry and
biology laboratories for general research are located on the first floor.
Approximately one third of floor space is reserved for cell culture
laboratories where layout is dictated by sterilisation procedures for people
and objects, before gaining access to areas for emergency and decontamination
protocol when needed.
Patient cultures are
situated on the second floor, predominantly cell culture laboratories with BLS3
contamination control protocols where the very high level of antiseptic
conditions required means the laboratory apears as a series of white rooms with
support areas.
-architectural project - core idea
The
project’s starting point was the creation of a shell featuring a surface
treatment of the “skin” with patterns whose geometry is based on the
morphogenetic formulas of the skin. The building is a volumetric solid with an
outer layer presenting shapes generated using a mathematical formula simulating
the formation of animal skins.
Reaction-diffusion
equation. The Vectorial equation gives the spatial and temporal dynamic for the
concentration of morphogen C. By assigning a colour to each C value a pattern
is obtained.
This
“skin” facade corresponds to two needs: first the need for a visual“language”
to represent activity inside the building; second it resolves a need for
flexibility and transformability in both the design phase and the fruition
phase by using a framework which can just as easily accommodate a window, a
grill or a panel.
The
project seeks to conceal engineering systems and technology housed within it
beneath the skin (there are 17 are treatment units alone) to offer an organic
image of soft technology.