In 2007, Jenny E. Sabin and Peter Lloyd Jones initiated LabStudio, a hybrid research and design unit based within the Institute for Medicine & Engineering, the School of Design and the Nonlinear Systems Organization at The University of Pennsylvania. Within the Sabin+Jones LabStudio, architects, mathematicians, materials scientists and cell biologists are actively collaborating to develop, analyze and abstract dynamic, biological systems through the generation and design of new tools. These new approaches for modeling complexity and visualizing large datasets are subsequently applied to both architectural and biomedical research and design. The real and virtual world that LabStudio occupies has already offered radical new insights into generative and ecological design within architecture, and it is providing new ways of seeing and measuring how dynamic living systems are formed and operate during development and in disease. Overall, the Mission of LabStudio is to produce new modes of thinking, working and creating in design and biomedicine through the modeling of dynamic, multi-dimensional systems with experiments in biology, applied mathematics, fabrication and material construction.